- Physical Sciences
CIDETEC Nanomedicine’s platform supports the development, manufacturing, and scale-up of biomaterials and nanomedicine systems for use in medical devices, drug delivery, and advanced therapies.
It covers the entire development cycle, from laboratory-scale material synthesis to pilot-batch manufacturing in classified cleanroom facilities, including biological validation through cell culture.
The platform works with polymer-based hydrogels (both natural and synthetic), lipid and polymeric nanoparticles, non-viral gene therapy vectors, bioactive implant coatings, and materials for 3D bioprinting. Active development areas include orthopedics, ophthalmology, and skin applications.
By integrating synthesis, scale-up, and biological characterization within a single facility, the platform helps shorten development cycles and provides regulatory support through to CE marking.
Equipment
- Synthesis reactors with capacities of up to 10 L
- High-pressure homogenizer
- Microfluidic reactors for continuous encapsulation
- Pilot-scale encapsulation plant
- Freeze-dryer (lyophilizer)
- Classified cleanroom facilities for pilot-batch manufacturing, suitable for working with gene therapy vectors
- Endotoxin testing and quantification equipment
- Cell culture laboratory equipped for cytotoxicity, biocompatibility, and transfection assays
- Physicochemical characterization equipment for biomaterials, including particle size, zeta potential, and rheology analysis
- Design and synthesis of biomaterials and nanostructured systems, including nanoparticles, hydrogels, liposomes, and coatings.
- Scale-up of lipid and polymeric nanoparticles for drug delivery.
- Development and scale-up of non-viral vectors for gene therapy.
- Formulation of functional antimicrobial and anti-inflammatory coatings for implants.
- Pilot-batch manufacturing in classified cleanrooms with endotoxin control.
- Biological validation through cell culture, including cytotoxicity, biocompatibility, and transfection assays.
- Physicochemical characterization of biomaterials and nanomaterials.
- Regulatory development support toward CE marking of Class I–III medical devices.
- Collaborative development and co-working during the prototyping and ideation phases of R&D projects.
CIDETEC
Eskuzaitzeta Industrialdea, Oianguren, 5, 20160 Zubieta - Donostia / San Sebastián, SPAIN
Biomaterials and Tissue Engineering:
- Biotechnology, Processes and Biological Systems
- Healthcare Technologies
Application sectors
- Pharmaceuticals and genetics
- Healthcare and medical devices
Industrial plan
- HAZI · Healthcare and Biomedical Industry
