Molecular Oncology Research groups

Strategic Objectives

• To understand the molecular pathogenesis of haematological diseases (and other types of cancer) and the translation of that knowledge to clinical environments.
• To identify and develop new biomarkers for cancer diagnosis and prognosis.

Main lines of research

• The identification and assessment of the utility of circulating microRNA/RNA as non-invasive cancer biomarkers.

• Identification of factors behind drug resistance and new therapeutic procedures to treat cancer by using coding viral libraries for siRNA/microRNA.
• Identification of new mutations on the site of target gene-microRNA interaction and in the sequence of the same microRNA associated with cancer.
• Characterisation of the target miRNA:mRNA interface in cancer.